302, 2020

CIS Pharma attends EMSO sarcoma symposium in Milano

Milano, Italy, Monday February 3 to Wednesday February 5, 2020 - CIS Pharma attends the sarcoma symposium of the European Society for Medical Oncology, EMSO, in Milano. The event is a highly specialized meeting bringing together medical minds working on these tumor types. The symposium offered a good platform for CIS Pharma to discuss its oncology pipeline with known oncologists [...]

2301, 2020

CIS Pharma team attends the World Economic Forum in Davos

Davos, Switzerland, Thursday, January 23, 2020 – CIS Pharma attends the World Economic Forum in Davos, Switzerland. The main interest is to meet with its tracking technology partner modum.io and to attend the event provenance and transparency held at the Hotel Intercontinental in Davos. Tools against counterfeiting and instruments to create transparency in the value chain are two key areas [...]

801, 2020

CIS Pharma’s polymer-drug carriers successfully loaded with Lu-177 and In-111

Bubendorf, Switzerland, Wednesday, January 8, 2020 - In several laoding experiments Lutetium-177 and Indium-111 were loaded to CIS Pharma’s polymer-drug carriers, at high efficiency reates. Labeling density was close the level of metal chelators contained in the polymer-drug carrier, verifying the diversity that is offered by the polymer-drug carrier approach by loading different numbers of therapeutics to the antibody. Normally, [...]

1212, 2019

CIS Pharma PEEK implant program has reached the first milestone

Bubendorf, Switzerland, Thursday, December 12, 2019 - A new method for the modification of PEEK surfaces was established that significantly increases hydrophilicity of the material surface. The novel method is a scalable and convenient process and can be tailored to the desired physical properties of the PEEK surface. In preliminary cell culture experiments the modified PEEK surfaces have shown positive [...]

912, 2019

CIS Pharma’s polymer-drug carriers to load radioisotopes show excellent performance in a multiparameter toxicity study

Bubendorf, Switzerland, Monday, December 9, 2019 - CIS Pharm has tested several of its new polymer-drug carriers to conjugate radionuclides in a multiparameter cytotoxicity study at Cyprotex, a CRO based out of the UK and known for its expertise in ADME-tox. No matter what the loading capacity for radionuclides, the polymer-drug carriers show no toxicity effects in cell culture models [...]

612, 2019

CIS Pharma Christmas event in Arlesheim on ice

Arlesheim, Switzerland, Friday, December 6, 2019 - The team of CIS Pharma sets out on sheer ice, armed with stone and broom. After a short introduction, we are ready to play Curling, the traditional sport from Scotland. Gradually, we know how to handle the 20 kg stones and the competition starts: In two teams we take turns sliding heavy, polished granite [...]

2211, 2019

CIS Pharma team attends Asia-Pacific vitreo-retina society congress

Shanghai, China, Friday, November 22, 2019 – CIS Pharma is attending the Asia-Pacific vitreo-retina society congress in Shanghai to meet potential partners for its technologies in eye care during the three-day conference in Shanghai China. The Congress is an established, first rate platform in the Asia-Pacific region for scientific exchange, research and discovery in the field of vitreo-retinal diseases and [...]

111, 2019

CIS Pharma successfully conjugated a model antibody to its polymer-drug carrier comprising radioisotopes

Bubendorf, Switzerland, Friday, November 1, 2019 - Within the scope of the proof-of-concept study at the Paul Scherer Institute, a number of polymer-drug carriers enabling the conjugation of different amounts of radioisotopes, were successfully conjugated to model antibody trastuzumab. The site-directed conjugation of the antibody with different polymer-drug carriers was nearly quantitatively. The required excess of polymer as well as [...]

2910, 2019

CIS Pharma and the University of Appplied Sciences present their bio-membrane project at the Nano-Tech Event in Baden

Baden, Switzerland, Tuesday, October 29, 2019 - CIS Pharma and the University of Applied Sciences, FHNW Muttenz, are giving a talk at the Nano-Tech Apèro of the Swiss Nanoscience Institute, SNI. During the annual event scientist from academia and the industry gather to exchange their latest learinings on the field of nanoscience. CIS Pharma presents its recent achievements in project [...]

2810, 2019

Actinium announces positive interim results of antibody-radionuclide conjugate Iomab-B pivotal trial

New York, USA, Monday, October 28, 2019 - Actinium Pharmaceuticals Inc. announced key interim findings from the pivotal Phase 3 SIERRA trial of Iomab-B, an antibody-radionuclide conjugate, including feasibility and safety data. The Study of Iomab-B in Elderly Relapse/Refractory Acute Myeloid Leukemia, SIERRA, is a 150-patient, Phase 3 pivotal trial that is studying Iomab-B, Iodine-131 conjgated to apamistamab, compared to [...]

509, 2019

CIS Pharma initiates a proof of concept program for its novel polymer-drug carriers tailored to radioisotopes

Bubendorf, Switzerland, Wednesday, September 5, 2019 - CIS Pharma has signed a research agreement with the Paul Scherer Institute, Switzerland. The program comprises an invitro and invivo program for the conjugation of novel polymer-drug carriers to a model antibody by site-directed conjugation strategy and the labeling with suitable radioisotopes for diagnostic and therapeutic use. The antibody-radionuclide conjugates based on CIS [...]

1907, 2019

CIS Pharma summer event at the Rhine Falls

Schaffhausen, Switzerland, Friday, July 19,  2019 - During our Summer Event we take a boat ride along the banks of the Rhine Falls in Schaffhausen. The spectacular falls offers a refreshing spray of water. Next stop is Stein am Rhein, a beautiful town known for its medieval half-timbered houses. By boat we get to Steckborn, a small town on the [...]

1006, 2019

FDA approves novel antibody-drug conjugate Polivy

Maryland, USA, Monday, June 10, 2019 - The U.S. Food and Drug Administration granted accelerated approval to Polivy - polatuzumab vedotin-piiq, Roche - in combination with the chemotherapy bendamustine and a rituximab product to treat adult patients with diffuse large B-cell lymphoma (DLBCL) that has progressed or returned after at least two prior therapies. Polivy is a novel antibody-drug conjugate, [...]

2504, 2019

CIS Pharma initiates a new R&D program in the field of PEEK implants

Bubendorf, Switzerland, Thursday, April 25, 2019 - In a new research program the surface of PEEK medical implants will modified to enhance osteointegration and soft-tissue compatibility. The modification is targeting the use of PEEK at the at the hard-to-soft-tissue interface such as in dental applications. PEEK or Poly-ether-ether-ketone has been used as an implant material in craniofacial application for several years. [...]

712, 2018

CIS Pharma Christmas event in Bern

Bern, Switzerland, Friday, December 7, 2018 - For the end of year event, the team of CIS Pharma sets out to Bern, the capital of Switzerland. Our city guide Domenico Bernabei carries his heart and soul on his tongue and quickly catches our attention with city anecdotes of the last four centuries. His knowledge and entertainment skills got him featured [...]

2211, 2018

CIS Pharma starts collaboration with the Paul Scherer Institute on antibody-radionuclide conjugates

Bubendorf, Switzerland, Thursday, November 22, 2018 - CIS Pharma has identified the group of Prof. Schibli and Dr. Behe from the Paul Scherer Institute, ETH,  as potential partners for its antibody-radionuclide conjugate program. A scientific program for CIS Pharma’s synthesis unit was elaborated to develop by Q2/2019 novel polymer-drug carriers compatible with established conjugation technologies at Paul Scherer Institute. Upon [...]

111, 2018

Nordic Nanovectors presents promising Phase 1 study results on its antibody-radionuclide conjugate Betalutin

Philadelphia, USA, Thursday, November 1, 2018 - Betalutin is an antibody-radionuclide conjugate, ARC, representing a combination of lilotomab for targeting CD37, a protein that specifically exists on the surface of non-Hodgkin’s lymphoma cells, with the beta particle-emitting isotope lutetium-177. The radionuclide is immobilized with the help of a metal chelator. During treatment Betalutin is internalized into the cells and its [...]

1810, 2018

Novartis successfully completes acquisition of Endocyte and its new antibody-radionuclide conjugate

Zurich, Switzerland, Thursday, October 18, 2018 - Novartis today announced that it has completed the acquisition of Endocyte, Inc., a US-based biopharmaceutical company focused on developing radioligand and CAR-T therapies for cancer treatment. With this Novartis can add the antibody-radionuclide conjugate 177-Lu-PSMA-617, a potential first-in-class therapy in Phase III development for metastatic castration-resistant prostate cancer to its portfolio. Novartis intends [...]

910, 2018

CIS Pharma team attends CPhI Worlwide 2018 in Madrid

Madrid, Spain, Tuesday to Thursday, October 9 to 11, 2018 – CIS Pharma is attending CPhI Worlwide to meet development partners and licensees during the three-day conference in Madrid. The team is setting out to meet face-to-face project partners and to source solutions for their innovation projects. As a number of meetings are scheduled we are kindly asking to confirm [...]

1109, 2018

CIS Pharma summer event in Basel

Basel, Switzerland, Tuesday, September 11, 2018 - During our Summer Event we dive into the multifaceted side of Basel, Kleinbasel, at the northern banks of the river Rhine. Our trip starts with a ride on the Rhine taxi, taking us on a trip over the river, along the Cathedral Münster up to the Powerstation in Birsfelden and back down to [...]

3008, 2018

Approval received for innovative vial adaptor, available now for market introduction

Bubendorf, Switzerland, Friday, August 30, 2018 – CIS Pharma announces the approval of a vial adaptor specific for the preparation and injection of intracameral cefuroxime. Consequently, the adaptor was produced and is expected to reach the market shortly. The development is innovative device that prevents the 10mg/ml cefuroxime sodium solution from particulate contamination, containing several 5-micron filters. After reconstitution of [...]

2308, 2018

Antibody-drug conjugate market with an estimated CAGR of 19%

New York, USA, Thursday, August 23, 2018 - The advancement in the medical technology is driving the global market for antibody-drug conjugates. Preclinical research, the increasing research activities on antibody therapies, more research on advanced drug discoveries, increasing research on oncology diseases, the growing collaboration between research institutes, and the increasing number of biopharmaceuticals and biotechnology companies are acting as [...]

1007, 2018

CIS Pharma initiates a new R&D program on antibody-radionuclide conjugates

Bubendorf, Switzerland, Tuesday, July 10, 2018 - Over the course of the past months, CIS Pharma has developed concepts and strategies to conjugate  radioisotopes onto its polymer-drug carriers. First syntheses results and tests with cold substances are promising and CIS Pharma is proactively searching for scientific collaborations in the field of antibody-radionuclide conjugates, nuclear oncology respectively. About [...]

2602, 2018

Intracameral cefuroxime launched in Europe

Bubendorf, Switzerland, Monday, February 26, 2018  - CIS Pharma’s licensee has launched intracameral cefuroxime across Europe. Among others, cataract clinics in France, Germany, Spain, Italy and Netherlands will be supplied with the product. The CIS Pharma team is proud that based on its development, thousands of patients are saved from going blind. CIS Pharma’s licensee has a strong market penetration [...]

702, 2018

CIS Pharma team attends Pharmapack 2018 in Paris

Paris, France, Wednesday to Thursday, February 7 to 8, 2018 – CIS Pharma is attending CPhI Worlwide to meet development partners and licensees during the two-day conference in Paris. The team is setting out to meet face-to-face project partners and to source solutions for their innovation projects. As a number of meetings are scheduled we are kindly asking to confirm [...]